Revista de Bacteriología y Parasitología

Abstracto

Patrón de resistencia antibacteriana de bacterias grampositivas aisladas en la UCI de un hospital de referencia en el sur de Mozambique

Filipe Antonio Mahaluca, Jahit Sacarlal, Sabiha Essack

Objective: To describe the resistance pattern of Gram-positive bacteria isolated from patients admitted to ICUs at Maputo Central Hospital (HCM) in 2017.

Methods: This was a cross-sectional, epidemiological, quantitative approach, with a retrospective analysis of secondary data, performed at the ICUs in Maputo Central Hospital.

Results: During the study, 179 cultures were found to be positive for bacteriological tests (127 Pediatrics ICU and 52 Adults ICU), of which 55 (30.7%) were Gram-positive bacteria. Antibiotic resistance was highest in isolates of Staphylococcus Spp. (89.5%), Enterococcus Spp. (63.1%), Staphylococcus aureus (46.4%), Streptococcus Spp. (38.9%). MRSA was prevalent in 21.2% (7/33), with 85.7% the Pediatrics ICU and 14.3% in the Adults ICU, which is very significant in a hospital environment. Beta-lactams presented high resistance indices to all Gram-positive cocci, with a higher prevalence of Staphylococcus Spp. and Enterococcus Spp. Glycoptides had an average resistance of 50%, with Vancomycin inhibiting the growth of all strains of Staphylococcus aureus and Enterococcus Spp.

Conclusion: Resistance to antibiotics in Gram-positive cocci is a persistent problem, with infection control, selective antibiotic pressure and continuous resistance monitoring being the important factors in its spread.