indexado en
- Abrir puerta J
- Genamics JournalSeek
- DiarioTOCs
- Directorio de publicaciones periódicas de Ulrich
- Búsqueda de referencia
- Universidad Hamdard
- EBSCO AZ
- OCLC-WorldCat
- Publón
- Fundación de Ginebra para la Educación e Investigación Médica
- pub europeo
- Google Académico
Enlaces útiles
Comparte esta página
Folleto de diario
Revistas de acceso abierto
- Administración de Empresas
- Agricultura y Acuicultura
- Alimentación y Nutrición
- Bioinformática y Biología de Sistemas
- Bioquímica
- Ciencia de los Materiales
- Ciencia general
- Ciencias Ambientales
- Ciencias Clínicas
- Ciencias farmacéuticas
- Ciencias Médicas
- Ciencias Veterinarias
- Enfermería y Cuidado de la Salud
- Genética y Biología Molecular
- Ingeniería
- Inmunología y Microbiología
- Neurociencia y Psicología
- Química
Abstracto
BRF2, a Biomarker in Cancer?
Jana Koo, Stephanie Cabarcas-Petroski and Laura Schramm
Approximately 1.6 million Americans will be diagnosed with cancer in 2014 and 0.6 million Americans will die from cancer, keeping cancer as the second leading cause of death in the United States. These cancer incidence and mortality statistics imply that early detection and intervention are crucial to increasing survival rates. A major
obstacle in cancer treatment is the complexity of identification of various combinations of mutations in tumor suppressors and oncogenes in specific cancers and in individuals. It is clear that we have yet to identify all proteins which may have oncogenic potential which can contribute to complications that can arise in designing new individual and tissue specific cancer therapies. Herein, we discuss the role of the RNA polymerase (pol) III specific transcription factor BRF2 in human cancers and its potential use as a biomarker for diagnosis and its potential role in determining appropriate cancer treatment regimens.