Effect of Nostoc Muscorum on the Immunity and Survival of Aeromonas Salmonicida Infected Mugil Cephalus

V. Ramamurthy, S. Chitra, & S. Raveendran

The aim of this study was to evaluate dietary dosages of Nostoc muscorum on the immune response and disease resistance against infections due to the opportunistic pathogen Aeromonas salmonicida, in fish fingerlings. Cyanobacteria, N. muscorum was incorporated into the diets of fish, Mugil cephalus (Mangrove snapper) fingerlings. Every 20 days, different biochemical, haematological and immunological parameters were analyzed. Superoxide anion production, lysozyme, serum bactericidal, serum protein and albumin were enhanced in cyanobacteria treated groups compared with the control group. After 60 days, fish were survival with Aeromonas salmonicida, and mortality percentage was recorded up to day 10 post-challenge. Survival decreased in control group (57%) up to day 10 after infection. However, this was increased in the N.muscorum treatment group, i.e. 85% survivability in the 500 mg N.muscorum /kg, 1gm N.muscorum /kg and 71% survivability in the 2 gm N.muscorum /kg, respectively. These results indicate that N.muscorum stimulates the immunity and makes Mugill cephalus more resistant to infection by A. salmonicida.