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Abstracto

Physiology of Agronaute Proteins and the Impact of Multiple Combined Stresses on Crop yield

Daniel De La Torre

Argonaute proteins square measure key players in each factor regulation (eukaryotes) and host defense (prokaryotes) working on fiber nucleic-acid substrates, past depends aboard pairing between a tiny low nucleic-acid guide and its complementary target sequences for specificity. To expeditiously scan nucleic-acid chains for targets, past diffuses laterally on the substrate and should bypass secondary structures also as super molecule barriers. Exploitation single-molecule FRET in conjunction with kinetic modelling, we tend to reveal that focus on scanning is mediate through loose protein-nucleic acid interactions, permitting past to slip short distances over secondary structures, also on bypass supermolecule barriers via intersegmental transfer.